Current Projects

Identify underlying circuits affected by Tremor and Rigidity in Parkinson’s disease and atypical Parkinsonism

• The goal of this study is to identify brain regions affected by tremor and rigidity in Parkinson’s disease and Progressive supranuclear palsy

• We are leveraging multimodal MRI such as resting state fMRI, diffusion MRI and T1-weighted imaging modalities

• We are creating a large scale database aggregated from several smaller datasets to see how these affected brain regions shift during the course of the disease

Deep Brain Stimulation in Parkinson’s Disease

• The goal of this study is to identify how deep brain electrode placement can positively impact motor and negatively impact cognitive functions in Parkinson’s disease patients

• We developed new methods to isolate electrodes and account for post-surgery brain shift in CT images relative to pre-surgical MRI imaging